S
M
T
W
T
F
S
29
64°
30°
30
73°
56°
31
79°
62°
1
69°
43°
2
77°
46°
3
78°
64°
4
76°
45°
5
49°
36°
6
57°
34°
7
46°
33°
8
65°
30°
9
75°
46°
10
70°
50°
11
62°
45°
12
80°
48°
13
78°
64°
14
82°
64°
15
81°
66°
16
76°
59°
17
82°
49°
18
71°
45°
19
56°
34°
20
54°
39°
21
75°
53°
22
75°
53°
23
80°
57°
24
79°
57°
25
72°
52°
26
70°
55°
27
66°
50°
28
62°
45°
29
62°
44°
30
63°
44°
1
65°
46°
2
66°
48°
Temperature Graph
°F
Avg. Hi
Avg. Lo
Actual Hi
Actual Lo
Forecast Hi
Forecast Lo
April Weather in Lake Santee
Lake Santee's April 2026 forecast shows daily high temperatures ranging from 54° to 80°, with overnight lows between 39° and 57°. The average high for April is 68° with an average low of 49°. AccuWeather's monthly forecast extends further ahead than any other source, with day-by-day RealFeel® Temperatures giving a complete picture of how April weather will actually feel in Lake Santee. See also: May | June | July.