Here are the latest updates, listed in eastern time, and the most important things you need to know about the coronavirus pandemic.

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Eli Lilly, an Indiana-based pharmaceutical company, announced what it described as proof of concept data from a Phase II clinical trial on Wednesday showing that an experimental drug may be beneficial for patients suffering from mild to moderately severe cases of COVID-19. A single dose of the drug, monoclonal antibody, was said to have helped infected patients recover more quickly from COVID-19 and avoid hospitalization. According to The New York Times, more than 450 patients took part in the study and they were given either the experimental drug or a placebo. Six percent of patients who received the placebo ended up being hospitalized while only 1.7 % of those who were given the experimental drug required hospitalization. The results of the trial have yet to be peer-reviewed or even published in a medical journal. "These interim data from the BLAZE-1 trial suggest that LY-CoV555, an antibody specifically directed against SARS-CoV-2, has a direct antiviral effect and may reduce COVID-related hospitalizations," Dr. Daniel Skovronsky, Eli Lilly's chief scientific officer, said in a statement. "The results reinforce our conviction that neutralizing antibodies can help in the fight against COVID-19."

This is the first treatment so far meant to help patients with less-than-severe coronavirus infections. Dr. Myron Cohen, director of the Institute for Global Health and Infectious Diseases at the University of North Carolina at Chapel Hill, told the Times the results of the trial were impressive. Cohen, who was not involved in the study, described the findings as “exciting” and “really compelling.” He added that the results are “the opening of a door” for other scientists working on similar antibody therapies.  

Good news for college football fans emerged on Wednesday when the Big Ten football conference announced that it will begin its football season on Oct. 24, ESPN reported. The conference is planning to play an eight-game schedule over an eight-week period, leaving the conference very little margin for any disruptions as the conference championship is scheduled for Dec. 19 – just a day prior to the selection for the college football playoff series. The conference had yet to release a revised schedule of games. As of Wednesday, fans are not expected to be in the stands at games, which will be played in campus stadiums. Back on Aug. 11, the Big Ten leadership voted 11-3 to postpone the season. The vote to reverse and start the season was unanimous, ESPN reported.

Coronavirus cases zoomed past the 5 million mark in India on Wednesday with the country recording more than 1 million of those new cases in September alone, according to The Associated Press. The country has recorded the second-most cases in the world, behind only the U.S. More than 82,000 have died from COVID-19 in India, third-most globally. News of the grim milestone comes days after at least 25 members of Parliament tested positive earlier this week as the legislative body was going back into session, NDTV reported. Despite the surged in cases and fatalities, the AP reported, government officials have no plans to institute another lockdown. Previously this year, India’s government implemented what was described as the world’s biggest lockdown.

Health authorities in Maine now say at least seven people have died as a result COVID-19 contracted after attending an August wedding that was deemed a coronavirus super spreader event, according to The Associated Press reported. More than 175 cases of COVID-19 were tied to a wedding reception held at the Big Moose Inn in Millinocket, a town with a population of about 4,500 located around 180 miles north of Portland. The wedding was in violation of the state guidelines on public gatherings, which were capped at 50. The AP reported that the outbreak at the wedding has been tied to several other outbreaks across the state, hampering efforts to control the spread. Nirav Shah, director of Maine's CDC, told the AP, "COVID-19, right now, is not on the other side of the fence. It is in our yards. The gains that Maine has made against COVID-19 are ones that could, and unfortunately can, be washed away.”

Last week saw an increase in deaths from the coronavirus compared to the week before, new data from the World Health Organization showed on Monday. For the week ending Sept. 13, the amount of deaths from the virus rose by 8% with over 40,600 new deaths reported. Despite the increase in deaths, overall new cases of COVID-19 have fallen last week by 3%. The Americas, including the U.S., Canada, Mexico, and parts of South America, saw a slight decline in new cases. Nearly 25,000 new deaths were reported in the region last week which brought the total to 508,705. Southeast Asia was the second-highest region for new cases with 687,119. There have been 28.9 million total cases of the coronavirus according to WHO.

Amid a year of coronavirus fears and setbacks, new projections released by consulting firm Deloitte forecast the holiday shopping season will be less robust than in recent years. Economists are now calling for what is known as a "K-shaped recovery" which is when a rebound is unevenly split between income groups. Since COVID-19 started spreading across the United States, many industries continue to get by relying on work-from-home employees. Meanwhile, other companies have seen sales tank as consumers continue to avoid eating out and taking vacations. Deloitte predicts that holiday sales will rise between 1% and 1.5% between November and January which is down from 4.1% growth in 2019. The growth could remain low if lower-income individuals remain cautious and nervous during the later parts of the year. Alternatively, the growth could grow to 2.5% or even 3.5% if higher income consumers gain more confidence during late 2020.

International tourism nosedived by 65% in the first half of 2020 compared to 2019, equating to an estimated $460 billion loss in export revenues. The data from the World Tourism Organization was released Tuesday, revealing the toll the pandemic had taken on international travel as the world begins easing travel restrictions. “Safe and responsible international travel is now possible in many parts of the world, and it is imperative that governments work closely with the private sector to get global tourism moving again,” UNWTO Secretary-General Zurab Pololikashvili said. According to the UN’s tourism body, it could take between two to four years for tourism to recover to their 2019 levels. Of the total 440 million international arrivals lost between the months of January and June of 2020, Asia and the Pacific were the hardest-hit of the regions, according to Reuters. Here’s a look at the percentage of drop in arrivals in each region.

• Asia and the Pacific: 72% 

• Europe: 66% 

• Africa and the Middle East: 57% 

• The Americas: 55%

Louisiana State University head football coach Ed Orgeron said Tuesday that most of his team has contracted COVID-19, according to ESPN. "Not all of our players, but most of our players have caught it," Orgeron said.  "I think that hopefully they won't catch it again, and hopefully they're not out for games." According to ESPN, Orgeron was asked to clarify the percentage of players who had tested positive but he couldn't provide an exact percentage. The Tigers, the defending national champions, are scheduled to begin the 2020 season Saturday, Sept. 26, against Mississippi State

A United Arab Emirates top crisis authority announced that the country has approved use of a Chinese coronavirus vaccine for emergency use on frontline health workers. The UAE's National Emergency Crisis and Disaster Management Authority (NCEMA) said 31,000 volunteers already participated in a clinical trial of the vaccine including 1,000 with chronic diseases, according to CNBC. Phase three is still ongoing, but the agency assured no unexpected side effects have been detected yet. The COVID-19 vaccine was developed by Chinese state-owned pharmaceutical company Sinopham. The vaccine was approved by NCEMA for emergency use after a set of standards were met and the clinical trials were complete. Mild side effects were found in volunteers such as a sore throat, but the agency assured a lack of serious side effects with the vaccine.

Infectious disease expert Dr. Anthony Fauci met with officials from Vermont to applaud the state’s efforts and comment on the possibility of a nationwide mask mandate. The idea, which has been floated by many, including presidential candidate Joe Biden, has gotten plenty of pushback and enough so that Fauci said it may not be worth it, according to WCAX. According to Fauci, the mandate “probably would not work” unless “the citizens of a particular state, a city, a county or what have you, are really in lockstep with the authority.” Fauci added that the main issue that would have to be addressed would be regarding enforcement of the mandate.

Approximately 422,200 students from the nation’s largest public school district in New York City have opted to go with remote learning, according to NBC New York. The city’s Department of Education announced that the 42% of students choosing remote was an uptick of 15% from two weeks ago. On Monday, Mayor Bill de Blasio said that a total of 55 school-based employees have tested positive for COVID-19, 45 of which are teachers. Nearly 17,000 employees were tested. "Some people will test positive. And those folks will immediately get support. After two weeks, those professionals will come back to work -- and they'll complete the entire school year," de Blasio said. "The same will happen with students. We have to remember that for the very small percentage of people who test positive for the coronavirus, it is a very temporary reality."

South Korea plans to spend $146 million to procure a coronavirus vaccine, in hopes supplying 60% of its population with the vaccine. The 30 million people that make up 60% of the countries population is much higher than the World Health Organizations target population of 20% for the most vulnerable people, according to Reuters. The European Union nations also agreed to a much lower amount of 40% of their populations. Prime Minister Chung Sye-kyun said in a cabinet meeting that while the goal is to get the entire population a vaccine, there is too much uncertainty currently. South Korea plans to buy 20 million doses of the COVAX vaccine which is expected to be enough for 10 million people. The country also plans to buy 40 million doses from private drug-makers.

Bill Gates doesn’t think any of the coronavirus vaccines that are being developed in the United States could be approved before the end of October, despite President Trump’s hints that a viable vaccine could be ready before the Nov. 3 election. Gates told CNN that he is hopeful that a breakthrough on the vaccine development could happen early next year. “I do think once you get into, say, December or January, the chances are that at least two or three will – if the effectiveness is there,” he said. He also added that the only vaccine that “might seek the emergency use of license by the end of October, would be Pfizer.” On Monday, Pfizer CEO Albert Bourla told CNBC that its coronavirus vaccine could be distributed to Americans before the end of the year if Phase 3 trials are successful. “We do see good antibody levels both in the phase one and the phase two, so we’re pretty hopeful,” Gates said of Pfizer’s trials. If approved by the Food and Drug Administration, Pfizer is ready to distribute “hundreds of thousands of doses,” Bourla said.

After a six-month break due to the coronavirus pandemic, hundreds of Bedouins gathered in Egypt’s Sinai Desert to race their camels, according to AFP. Camel racing is a popular traditional sport in many Arab countries, specifically in the Gulf region. Unfortunately, races had to be suspended since March due to the outbreak of COVID-19 in the area. Last weekend, all races were allowed to resume, and more than 500 camels ran around a 1.2-mile track in the Tih plateau, as they competed in preparation for the international race, which should take place on October in Sharm el-Sheikh. “When I heard they were organizing the race again, I told my friends how crazy, how wonderful it is… We had to come,” Mostapha Abu al-Fadlt, a geologist from Cairo who was among the audience, told AFP. To the Bedouins, camel racing is a way to keep their tradition alive. “There was camel racing in the past, but we revived it,” Sheik Hassan, of the Alegat tribe, said. “Camels will not disappear for us. We can use them for centuries. If the camel goes away, the Bedouins will also go away.”

While the timeline over a COVID-19 vaccine may be vague, scientists urge that another way we can overcome the pandemic is with the flu shot. As officials from the Centers for Disease Control and Prevention warn of a possible “worst fall” in public health history, doctors are saying this year’s flu shot could be that nightmare’s best defense. According to Good Morning America, there were an estimated 500,000 hospitalizations from the flu last year, however if just 5% more people were to receive their flu shot, the CDC estimates that nearly 483,000 infections could be avoided. Those avoided hospitalizations would save crucial hospital beds and much-needed resources for a possible resurgence of COVID-19 cases.

A sign advertising flu shots is displayed on Tuesday, Sept. 8, 2020, in Ogden, Utah. The annual flu season is gearing up alongside the coronavirus pandemic, and Utah health officials are encouraging people to get their flu shots. (Tim Vandenack/Standard-Examiner via AP)

A human-like robot named Pepper is your latest reminder to wear your mask properly. The robot, engineered by the company SoftBank Robotics, scans individual faces to detect whether people are wearing masks properly. If they are not, the robot politely asks them to put one on correctly. According to Reuters, the robot is already in function at some shops and public exhibitions. “We’re all human. Sometimes I take off my mask when I get off the bus and I forget to put it back on when I arrive at the office,” Jonathan Boiria, head of sales in Europe for the company, told Reuters. “The robot provides a reminder. We can all get it wrong or forget.”

China could have a coronavirus vaccine ready for use by the general public as early as November, according to an official with the Chinese Center for Disease Control and Prevention. Currently, China has four COVID-19 vaccines in the third and final stage of clinical trials. Based on the success of the trials, CDC chief biosafety expert Guizhen Wu said that one of the vaccines could be ready for the general public in November or December. Chinese pharmaceutical giant Sinopharm is developing three of the vaccines and said that a potential vaccine could be ready for the public after the conclusion of Phase 3 trials, which are currently underway, according to Reuters.

Researchers at the University of Pittsburgh made an antibody discovery that could potentially treat and even prevent COVID-19. According to the Pittsburgh Post-Gazette, a team of researchers at Pitt School of Medicine found the smallest biological molecule to date that “completely and specifically” neutralizes the SARS-CoV-2 virus. The antibody, which is 10 times smaller than a full-sized antibody, can be used to create a drug called AB8, which was found to be “highly effective” at preventing the coronavirus in mice and hamsters, according to a report published on Monday in the journal cell. “Ab8 not only has potential as therapy for COVID-19, but it also could be sued to keep people from getting SARS-CoV-2 infections,” Dr. Mellors, chief of the Division of Infectious Diseases at UPMC and Pitt, said. “Antibodies of larger size have worked against other infectious diseases and have been well tolerated, giving us hope that it could be an effective treatment for patients with COVID-19 and for protection of those who have never had the infection and are not immune.”

Here are the latest COVID-19 numbers, provided by researchers at Johns Hopkins University:

• Confirmed cases: 29,303,757

• Fatalities: 928,963

• Recoveries: 19,880,425

Spain recorded 27,404 new cases on Monday, marking its most severe one-day increase since the beginning of the pandemic. The nation has seen the ninth-most cases in the world and the most of any western European country.

A ‘hug curtain’ is allowing residents at a nursing home in San Salvador, El Salvador, to hug their loved ones. The pandemic has forced many elderly people around the world into isolation as nursing homes in particular have become hotspots for disease transmission. According to geriatrician Luis Bermudes, anxiety levels and the amount of medication used have both decreased “when there is physical contact between a family member and the resident,” according to AFP. Thus far, El Salvador has recorded over 27,000 cases of nearly 800 deaths, according to Johns Hopkins University.

As a second wave of coronavirus infections threatens Europe, six countries have started testing technology to link national virus-tracing apps across the continent. According to AFP, the European Commission said that the Czech Republic, Denmark, Germany, Ireland, Italy and Latvia have started testing links between their tracking app servers. The new system “will ensure that apps will work seamlessly also across borders,” the EU executive said. “Users will only need to install one app and will still be able to report a positive infection test or receive an alert, even if they travel abroad,” the commission said. Currently, Brussels is seeking to coordinate between the 27 EU capitals, so that all countries can build compatible apps, which will help improve contact tracing and control new outbreaks. Many member states, including France and Hungary, have already built contact-tracing apps that are not compatible with the EU system. However, apps used in 18 EU members, including Germany, Poland and Italy can be involved. “Travel and personal exchange are the core of the European project and the single market,” said Thierry Breton, the EU’s Industry Commissioner. “The gateway will facilitate this in these times of pandemic and will save lives." 

An analysis published by JAMA Pediatrics on Monday suggests that adults are nearly 10 times more likely to be asymptomatic carriers of COVID-19 than children. According to the study, only around 1% of children who had no symptoms tested positive for the virus after they were admitted to a hospital in Milan. The percentage is low when compared to more than 9% of asymptomatic adults who tested positive for COVID-19. “The data do not support that children may be asymptomatic carriers more than adults,” study co-author Dr. Carlo Agostoni, a pediatrician at the University of Milan, told UPI. Over the past months, researchers have estimated that between 50% and 80% of individuals infected with the virus are asymptomatic, while symptomatic children may be up to 15% of those carrying COVID-19. 

There have been at least 6,545,948 cases of coronavirus in the U.S., and at least 194,367 people have died, according to Johns Hopkins University's tally of cases in the United States. The totals include cases from all 50 states, the District of Columbia and other US territories, as well as repatriated cases. 

France adds new limits on public activities cases rise

Marseille and Boudreaux are tightening restrictions on public activities as COVID-19 infection rates continue to increase, according to The Associated Press. The stricter restrictions announced on Monday are a response to France’s prime minister, who urged the cities to take additional steps to control the spread of the virus. In Boudreaux, the top government official for the region announced a ban on gatherings of more than 10 people at the city’s public parks, as well as at the river and beaches. In addition, the city’s cafes and restaurants will not serve clients who are standing up. Dancing and alcohol consumption are now also forbidden at public venues. In Marseille, the regional government also announced similar restrictions, along with the cancellation of an 11-day international festival.

South Carolina’s lieutenant governor tests positive for COVID-19

South Carolina Lt. Gov. Pamela Evette tested positive for the coronavirus on Friday, officials said. According to The Associated Press, Evette was tested on Thursday, as she was experiencing a sore throat and a headache. Since then, she has stayed at home with her family and is now recovering, according to Brian Symmes, the spokesman for Gov. Henry McMaster. “She is feeling better now,” Symmes said. He then added that Evette plans to remain in isolation for the next two weeks. On Monday, Evette shared her experience on social media and urged those who are experiencing symptoms to take the necessary precautions. “If you’re showing any symptoms at all, the best thing to do is to get tested right away! There are testing sites readily available all across the state,” Evette wrote on Twitter. 

At 1,401 feet tall, One Vanderbilt is now the second-tallest office tower in New York City after the skyscraper opened Monday in midtown Manhattan. Only One World Trade Center, in lower Manhattan, is taller. But the prospects surrounding tenants for the new tower, located right next to Grand Central Terminal, are less certain due to the coronavirus pandemic. Many office workers are still working remotely and, according to Reuters, the tenants that have already signed on to lease office space in One Vanderbilt won't be able to actually move in until later this year. Reuters reported that 67% of the building's office space has been leased at a price of $100 per square foot. But the overall real estate market in the Big Apple is on shaky ground as the city was the epicenter of the outbreak in the U.S. during the early stages of the pandemic. Unemployment in the city shot up to 20%. According to Reuters, the fallout from that has meant that more than 70% of leases are sublets and short-term leases. The building opened Monday and, in a sign of the times, was welcomed with a socially-distant ribbon cutting. The weather couldn't have been any more pleasant in midtown, with a high in the mid-70s, but, judging by pictures from the event, the ribbon-cutting didn't look quite as socially-distant as it was billed.

The pandemic has disrupted nearly everything to some degree this year, and that is now true for a beloved annual Thanksgiving Day event that takes place in New York City. "For the first time in its more than 90-year history, the annual Macy’s Parade will be modified to safely bring the magic to more than 50 million viewers nationwide on Thanksgiving Day, while maintaining all of the spectacle and wonder of this cherished holiday tradition," Macy's said in a statement on Monday. "This year the celebration will shift to a television-only special presentation." This year's edition of the parade will be the 94th and parade organizers said the health and safety of participants and spectators is the top priority. According to the statement, some of the changes parade organizers are making this year include:   

• Reducing the overall number of participants by approximately 75%, and splitting the remaining participants over two days

• All participants will be appropriately socially distanced during performances and be required to wear face coverings and additional personal protective equipment depending on their role

• No participant in the parade will be under 18 years of age• Macy’s signature giant character balloons will be flown without the traditional 80-100 handlers and instead employ an innovative, specially rigged anchor vehicle framework of five specialty vehicles tested and approved by the NYCDOT and NYPD

Mask up! That was the message from the league to coaches and sideline staff after the NFL's first slate of Sunday games played during the coronavirus pandemic was in the books. Numerous sideline staff and coaches were seen Sunday not wearing face coverings, in violation of league policy. Sean McVay, head coach of the Los Angeles Rams, was seen not wearing a mask during a game broadcast Sunday night in prime time on national TV. There were others as well. "We must remain vigilant and disciplined in following the processes and protocols put in place by not only the league, union and clubs, but also by state and local governments," Troy Vincent, a former player who now heads up the NFL's football operations, said in a memo to teams on Monday, The Associated Press reported. “Failure to adhere to this requirement will result in accountability measures being imposed against offending individuals and/or clubs,” Vincent said in the memo, according to the AP. “The face covering must be worn as designed so that it securely fits across the wearer’s nose and mouth to prevent the transmission of the virus.”

Los Angeles Rams head coach Sean McVay yells out instructions during the first half of an NFL football game against the Dallas Cowboys Sunday, Sept. 13, 2020, in Inglewood, Calif. (AP Photo/Jae C. Hong )

(AP Photo/Jae C. Hong )

According to a report by Bloomberg, a new study claims emerging coronavirus hotspots could be predicted by analyzing Google search keywords related to digestive problems. Researchers from Massachusetts General Hospital analyzed data from Google Trends covering a period from Jan. 20 to April 20 and looked at the number of searches for various symptoms that are often reported by people who test positive for COVID-19, including diarrhea and loss of taste and appetite. According to their findings, published in the Clinical Gastroenterology and Hepatology, the highest number of searches for those symptoms corresponded to a rise in cases over the next three to four weeks in five states: New York, New Jersey, California, Massachusetts, and Illinois. New Jersey and New York were two of the hardest-hit states in the earliest stages of the pandemic. "Our results suggest that increased search volume for common GI symptoms may predict COVID-19 case volume, with 4 weeks as the optimal gap between increase in search volume and increased case load," the researchers said in the study. They added that more research is need before a predictive model could be created based on this concept.

As the race for a coronavirus vaccine heats up, one big pharma CEO said his company is now only weeks away from knowing whether its developmental drug will be effective or not. Albert Bourla, CEO of Pfizer, appeared on CBS' Face the Nation on Sunday for a wide-ranging discussion with Margaret Brennan about the pharmaceutical company's development of a COVID-19 vaccine. Bourla said the company has a better than 60% chance "that we will know if the product works or not by the end of October. But of course," he cautioned, "that doesn't mean that it works. It means that we will know if it works." Bourla also revealed the drugmaker is planning to widen the scope of the types of patients it's testing the developmental vaccine on and raise the total number of those tested to 44,000. "Right now, the study recruits from 18 to 85. Now we will go to 16 years old," the CEO said. "Also, we will go to people with special conditions, chronic conditions like HIV patients, but also we will try to use it to increase the diversity of the population." Watch a clip from the appearance below. 

The Global Preparedness Monitoring Board issued a scathing report criticizing world leaders for inadequate action prior to the coronavirus pandemic that has left all of humanity "paying the price." The group, a panel that oversees global preparedness and accountability for health crises, issued the report, titled "A World in Disorder," in recent days. “It is not as if the world has lacked the opportunity to take these steps,” the report said. “There have been numerous calls for action ... over the last decade, yet none has generated the changes needed.” One of those warnings came from the GPMB itself last year, months before the coronavirus outbreak occurred in China. The panel's 2019 report warned of "a rapidly-spreading pandemic due to a lethal respiratory pathogen." The report went on to predict that millions could die and the global economy would be thrown into turmoil. Moreover, the panel said the coronavirus pandemic has cost the world $11 trillion and will cause another $10 trillion in economic damage before it's all over. "Pathogens thrive in disruption and disorder. COVID-19 has proven the point," the report said. The panel also offered some lessons learned and five calls to action that politicians around the world must take to mitigate any further damage. Read the full report here.

A top official at the WHO said the death toll in Europe is expected to spike again in October and November. Hans Kluge, the top official at the organization's European branch, told AFP that the current rise in cases will be one factor that leads to more fatalities along with uncertainty about how effective a vaccine will be. "It's a moment where countries don't want to hear this bad news, and I understand," Kluge said in the AFP interview. "I hear the whole time: 'The vaccine is going to be the end of the pandemic'. Of course not!," he continued, adding, "We don't even know if the vaccine is going to help all population groups. We are getting some signs now that it will help for one group and not for the other." Several European countries are reporting new cases at a higher clip than at the worst point in April, but the death toll has not been sharply rising in recent weeks. Kluge cautioned that will change. "It's going to get tougher. In October, November, we are going to see more mortality," he said.

Here are the latest global coronavirus numbers, provided by researchers at Johns Hopkins University:

• Confirmed cases: 28,855,994

• Fatalities: 921,698

• Recoveries: 19,511,976

Israel is entering a second lockdown as cases begin to spike in the country once again. Prime Minister Benjamin Netanyahu announced the lockdown on Sunday night, which includes the closure of schools, stores, malls and hotels, according to The Washington Post. Additionally, the lockdown will impose restrictions on travel for at least three weeks. “Our economy is still in a good shape,” Netanyahu said. The country originally opened in May, but health officials are now concerned about the significant rise in cases and have urged stricter measures to return for the country of nine million. “We are preparing in advance, closing down, so we can get out ahead of the virus,” Netanyahu said. The lockdown announcement comes ahead of the winter months full of holy Jewish celebrations. “It will be a different kind of holiday this year. We will not be able to celebrate like we usually do with our families.”

North and South Dakota are now the hotspots for infection rates in the U.S. with cases growing rapidly as the debate on mask-wearing gets more and more heated for the two states. The Governors of both states have steered clear of any statewide mask mandates and largely left the decisions to local governments. In Brooklings, South Dakota, a City Council meeting had to be moved to a nearby arena as residents poured in to voice their disagreement with a proposed requirement for face coverings inside businesses. “It is not a surprise that South Dakota has one of the highest [COVID-19] reproduction rates in the country,” Brookings City Councilman Nick Wendell said in reference to the large number of residents who rejected mask-wearing, according to The Los Angeles Times. Health experts are now growing concerned that the two states may overwhelm their healthcare systems before the virus is able to be contained. In North Dakota, 22% of coronavirus tests came back positive. Native Americans have been largely affected by the pandemic and account for 24% of deaths in the two states. While cases grow, those opposing mask mandates in the states say requiring a face covering would be a violation of their rights. “There are a lot of things we have in life that we have to deal with that cause death,” business owner Teresa Haldeman told the council in Brooklings. “We live in America, and we have certain inalienable rights.”

Halloween, Valentine's Day and Christmas will be missing one sweet treat this year as an unexpected consequence of the coronavirus pandemic. Just Born Quality Confections announced that the production of their iconic Peep marshmallow candies will be on a hiatus for a few months as they prepare for Easter, meaning they will not be producing seasonal editions of their candies for other holidays this year and into early 2021. The production of the candies were originally halted in the spring when the coronavirus first began to spread in Pennsylvania where the company is based. “This situation resulted in us having to make the difficult decision to forego production of our seasonal candies for Halloween, Christmas and Valentine’s Day in order to focus on meeting the expected overwhelming demand for Peeps for next Easter season, as well as our everyday candies,” the company said, according to NBC 10 Philadelphia.

The Phase Three trial of AstraZeneca's developmental COVID-19 vaccine is back on after being halted earlier this month when a patient who was receiving the vaccine reported experiencing neurological symptoms. According to Reuters, medical safety regulators overseeing the trial gave the pharmaceutical company the go-ahead to resume the trial, which is being conducted at Oxford University in England. The side effect the patient suffered was linked with transverse myelitis, a rare spinal inflammatory disorder, Reuters reported. AstraZeneca has said it could supply 3 billion doses of the vaccine if it passes the trial. Watch more in the video below. 

A new study suggests that the new coronavirus can actually "hijack" a person's braincells and use them to duplicate themselves. The study, which was published in bioRxiv, has not yet been published in a peer reviewed journal, but it provides evidence that the coronavirus can impact the neurons in the brain. The virus has already been linked to other brain damage, such as inflammation that can turn deadly and brain diseases called encephalopathies, according to Live Science. "We are actively looking at more patient tissues to be able to find how frequently such brain infections occur ... and what symptoms correlate with infection of which areas of the brain," senior author and immunologist at Yale University, Akiko Iwasaki, told Live Science. Scientists are yet to understand how the virus enters the brain and if it is preventable.

Here are the latest global coronavirus numbers, provided by researchers at Johns Hopkins University:

• Confirmed cases: 28,593,293

• Fatalities: 917,321

• Recoveries: 19,288,172

Six men in Oxford, Ohio, were cited last Saturday after testing positive for the coronavirus and attending a house party near Miami University anyway. The citations were issued due to violations of Ohio's mass gathering and quarantine ordinances. According to USA Today, body cam footage from the police officers shows the officers approach the house with unmasked men on the porch, one of the men then tells an officer he had tested positive for the coronavirus, along with everyone else at the house. "If students could witness the death and devastation inside ERs and ICUs over the past few months, they might better understand the value of not only quarantines and isolation if they test positive, but the possibility of death if they attend or hold a party if they have COVID-19," Robert Glatter, an emergency physician at Lenox Hill Hospital, in New York City, said in response to the incident.

On Friday, Director of the National Institute of Allergy and Infectious Diseases Anthony Fauci made some grim remarks in regards to the state of normalcy returning to the U.S. when the pandemic subsides. "If you're talking about getting back to a degree of normality which resembles where we were prior to COVID, it's going to be well into 2021, maybe even towards the end of 2021," he said. While he has said it is possible for one of the vaccines currently in development could get emergency use authorization by the end of the year, he said the bigger hurdle will be the distribution of vaccines, according to CNN. "By the time you mobilize the distribution of the vaccinations, and you get the majority, or more, of the population vaccinated and protected, that's likely not going to happen to the mid or end of 2021," he said.

Administrators at the University College Roosevelt in Middelburg, Netherlands, a small town near the English Channel about two hours from Antwerp, Belgium, have begun trying open air classes as a way of reducing the risk of coronavirus transmission while still holding in-person lectures, AFP reports. Edward Nieuwenhuis, professor of biomedical and life sciences said, “We have a lot of locations where we can teach in the open air so that we can have the whole group together with sufficient distance.” He added that the open air class idea is meant to avoid the pitfalls of holding classes via Zoom, the popular video-conferencing application that has exploded since the pandemic began. As for students, they seem to like it, but one said that being mindful of the weather is important. Anje Boswijk said, "Just be aware it might be a little bit cold, so dress appropriately, bring layers. And furthermore, I think it's important to stay engaged, because it is also a little bit more distracting to be outside maybe because there are other people walking around." Watch the video below for more:

A new poll has found that the mental health of young Americans under 35 years old has taken a drastic hit due to the coronavirus pandemic. The COVID Response Tracking Study conducted by NORC at the University of Chicago found that 56 percent of Americans ages 18 to 34 say they have at least sometimes felt isolated in the past month, while just 4 in 10 older Americans reported the same. According to The Associated Press, the study also found that 25 percent of young Americans rate their health as fair or poor, which is significantly higher than the 13 percent reported by older Americans. Young adults are in the midst of navigating life into college or careers without the experience of normal social activities that are essential for growth, the AP reported.

For more than three months, Thailand reported zero new cases of COVID-19, but two new cases have been confirmed in as many weeks. The first was reported last week in the capital of Bangkok, followed by a man testing positive on Friday. In the latest case, the man had tested negative three times after traveling abroad, but later contracted the coronavirus, Reuters reported. One possibility is that the virus had an incubation period of longer than 14 days, virology expert Kong Poovorawan said. Everyone that was in contact with the man has tested negative for COVID-19, but are still undergoing quarantine, Reuters reported. Since the start of the pandemic, Thailand has restricted travel into the country to only Thai nationals and approved foreigners, which has helped to keep the total number of cases in the country under 3,500. 

After being postponed one year due to the coronavirus pandemic, Japan’s Olympic Minister Seiko Hashimoto and International Olympic Committee (IOC) officials announced that the 2021 Olympic Games will take place. Hashimoto said that the Summer Olympics in Tokyo will be held “at any cost,” according to UPI. "Everyone involved with the Games is working together to prepare, and the athletes are also making considerable efforts toward next year," Hashimoto added. There are still many uncertainties surrounding the Summer Olympics next year, but officials are working hard to ensure that the event is not postponed or canceled due to the pandemic. “Now very much these will be the Games that conquered COVID-19 -- the light at the end of the tunnel,” IOC vice president John Coates said.

Schools across the world faced the same dilemma this month —  how to safely return children to school amid the coronavirus pandemic. In Spain, for example, staff members and students over the age of six are all required to wear face masks, remain in “social bubbles” and wash their hands six times a day. Additionally, they have placed a ban on ball games, according to Reuters. Spain also has designated lunch chairs, so students sit in the same place every day. In Iran, officials have opted for students to come to school adorned in face shields. Students’ temperatures are checked each day and their shoes are disinfected upon arrival. “We were worried,” Ms. Khooban, a mother of an Iranian student, said. “I did my best to teach my child how he should observe health protocols. I think its better for first grade students to attend school in person.” In Bosnia-Herzegovina, the village of Kacuni built an “open-air” classroom for its students to learn outdoors, however it is restricted in use depending on weather. In Nice, France, masks are required only for students aged 11 or older. Classrooms are ventilated and disinfected throughout the day. Primary schools have split classes to 8-15 students, and the students alternate in half days, where they spend the other half the day learning from home. Secondary school students have to attend school a few days a week. “I am happy because I will see all my friends again and get back to work,” student Gabriel Salandre told Reuters. 

Some scientists believe face masks may work as a stand in for vaccines. Universal use of face masks may help reduce the severity of the coronavirus and allow a larger amount of new infections to be asymptomatic, meaning it could potentially create a new form of “variolation,” or immunity, and ultimately contribute to a slowed spread of the virus across the U.S. The possibility first became apparent in March, when patients with no symptoms were reporting viral shedding from their noses at the same rate as those that were presymptomatic or symptomatic. According to an article published by The New England Journal of Medicine, the use of universal face coverings seems to potentially be an effective method in preventing spread from infected individuals who are asymptomatic. “The most obvious way to spare society the devastating effects of COVID-19 is to promote measures to reduce both transmission and severity of illness,” the article states. In order to properly test the hypothesis that population-wide mask wearing could be an effective method, scientists need to compare side-by-side the rate of asymptomatic infections in areas both with and without universal mask mandates. Experts not included in the article, however, are hesitant to jump on board with this theory without proper proof. “It seems like a leap,” Saskia Popescu, an infectious disease epidemiologist, told The New York Times. “We don’t have a lot to support it.”

The release of the highly-anticipated superhero movie Wonder Woman 1984 has been delayed yet again due to the coronavirus. The movie, which was originally set to be released in theaters over the summer, is now set to hit the the big screen on Christmas Day, The Associated Press (AP) said. The big-budget superhero movie is being delayed in part so that more theaters will be open and available to show the film. About one-quarter of all theaters in the U.S. remain closed, including in big cities such as Los Angeles, The AP said. “We’re very proud of the film and look forward to bringing it to audiences for the holidays,” Warner Bros. chairman Toby Emmerich said.

The NFL kicks off this weekend and many teams will not have fans in the stadiums due to the coronavirus, but that does not mean that the stands will be empty. The Baltimore Ravens have dedicated a part of  M&T Bank Stadium to Mo Gaba, a superfan who passed away earlier this year at the age of 14. Gaba was blind and battled cancer four times before passing away in July, CNN reported. In 2019, Gaba became the first person to announce an NFL draft by reading the selection that was written in Braille. The Ravens filled all 575 seats in section 146 with cardboard cutouts of Gaba, according to Fox Fox 45, with a sign above the section reading “Mo’s Rows.”

Infectious-disease experts are warning that a potential surge in coronavirus cases may cause a second wave of infections and deaths from a "cold-weather surge." The second wave could be at catastrophic levels and may even begin during autumn, The Washington Post reported. Since early in the pandemic, researchers and experts have hypothesized an autumn surge for the coronavirus based on patterns from other respiratory viruses. Respiratory viruses typically transmit more easily a couple of weeks after classes resume. Viruses also tend to spread more easily in cooler and less humid conditions, which may contribute to a significant surge in cases in the coming months. A recent model published by the University of Washington's Institue for Health Metrics and Evaluation showed early November to have a "most likely" death toll of 1,907 and could peak at nearly 3,000 by early December. The model also projects 410,000 people will have died by 2021 in a "most likely" scenario.

France has broken its record for most cases in a day after the country reported nearly 10,000 positive COVID-19 results in the last 24 hours. The health ministry reported a total of 9,843 new cases and 71 new clusters, according to France24. The increasing concerns over the rising number of infections has prompted French minsters and health experts to meet on Friday to discuss what additional measures may be needed to prevent further spread. In the last week, more than 48,500 cases have been reported in France. Jean-François Delfraissy, head of the scientific council, warned the government that they needed to make tough decisions and soon including imposing lockdowns.

A medical crew gathers around a patient affected with COVID-19 in a Marseille hospital, southern France, Thursday, Sept.10, 2020. As the Marseille region has become France's latest virus hotspot, hospitals are re-activating emergency measures in place when the pandemic first hit to ensure they're able to handle growing new cases. (AP Photo/Daniel Cole)

(AP Photo/Daniel Cole)

Among a number of social activities, including working at an office, visiting a salon and shopping in person, no activity appears to heighten the risk of contracting COVID-19 like dining at a restaurant or drinking at a bar. According to a report from the Centers for Disease Control and Prevention, “Adults with confirmed COVID-19 were approximately twice as likely as were control-participants to have reported dining at a restaurant in the 14 days before becoming ill.” The analysis compared 154 case patients, infected symptomatic adults, with 160 control patients, adults with negative test results. "In addition to dining at a restaurant, case-patients were more likely to report going to a bar/coffee shop, but only when the analysis was restricted to participants without close contact with persons with known COVID-19 before illness onset. Reports of exposures in restaurants have been linked to air circulation,” the CDC report stated.

In May, air quality expert Dr. William Bahnfleth told AccuWeather that poor air ventilation and a lack of outside air recirculation can lead to increased contagion concentration, thus raising the infection risk in places such as restaurants, evidenced by the virus spread at a Guangzhou, China, restaurant in January.

Coughing, shortness of breath and even loss of taste have all been symptoms connected with COVID-19. But cracked teeth? According to one dental practitioner, emergency fracture appointments have been on the schedule every single day since reopening in June. According to a New York Times op-ed written by Dr. Tammy Chen, phone calls for jaw pain, tooth sensitivity and mouth pain spiked immediately after stay-at-home orders were enacted in March. According to Chen, the main teeth-breaking factors are likely from stress, poor posture and a lack of restorative sleep. “From COVID-induced nightmares to “doomsurfing” to “coronaphobia,” it’s no secret that pandemic-related anxiety is affecting our collective mental health,” she wrote. “That stress, in turn, leads to clenching and grinding, which can damage the teeth.”

The NFL season kicked off Thursday night in Kansas City with a game between the Chiefs and the Houston Texans. Signs of the pandemic abounded, including a smattering of fans in the stands who were all properly socially distanced. Masks were a staple among coaches and staff on the sidelines. And then there was Kansas City head coach Andy Reid’s face shield, which drew much attention on social media. The weather at the game was unseasonably cool, with temperatures in the 50s on Thursday night, and a little wet. The weather inside Reid’s face shield was foggy. Very foggy. The shield was reportedly custom-made and connected to the hat he was wearing, but it clearly didn’t work out – something he acknowledged after his team’s 34-20 victory. "I didn't do very good with that thing," Reid told reporters, according to CBS Sports. "It will be better with that next time. It will be fixed." People on social media, however, loved the foggy situation and posted all sorts of quips and memes on Twitter during and after the game. As one Twitter user pointed out, maybe the defending Super Bowl Champion coach doesn’t even need to see the game his team is playing to defeat the opponent.

Here are the latest COVID-19 numbers, provided by researchers at Johns Hopkins University:

• Confirmed cases: 28,200,037

• Fatalities: 910,134

• Recoveries: 19,020,846

Another day, another daily record for the country with the second-most total COVID-19 cases. India recorded 96,551 new cases on Thursday, breaking the daily record the country had set just 24 hours earlier. The nation has reported at least 75,000 new cases each day this month, pushing their national total to over 4.5 million.

The U.S. needs to “hunker down” this flu season due to COVID-19, according to Director of the National Institute of Allergies and Infectious Diseases Dr. Anthony Fauci. According to NBC News, Fauci spoke alongside a panel of doctors from Harvard Medical School, where they discussed the direction the country may be headed as people prepare for flu season.Fauci also discussed the possibility of Labor Day surges in new cases, and said that as one region of the U.S. gets the virus under control, a hot spot emerges elsewhere. “We need to hunker down and get through this fall and winter, because it’s not going to be easy,” Fauci said. “Don't ever, ever underestimate the potential of the pandemic. And don't try and look at the rosy side of things."

Microsoft has teamed up with the NFL to allow fans to cheer their teams on virtually. Using Microsoft Teams, football teams will be able to see their fans on giant screens in the end zone when they score to give both fans and players the opportunity to celebrate together. In 2013, Microsoft and NFL entered into a technological partnership. The new use of Teams during the games is an extension of that partnership. “Part of watching a game on TV is seeing fan reaction. This is a chance to make the games more engaging for that TV audience,” Jeff Teper, the Microsoft corporate vice president in charge of Teams, told CNBC. 

A primary school in the Basque Country region of Spain was forced to close after many teachers tested positive for the coronavirus. After a shutdown spanning six months, students began returning to classes. It did not take long, however, for cases to start popping up in schools across the country. “We have 28,600 schools...and as of yesterday we had incidents in 53,” Education Minister Isabel Celaa said. “This means that school management and administrative staff have done a spectacular job.” According to Reuters, only a handful of individual classes throughout the country were sent home due to cases emerging without the need for larger intervention, but the primary school located in the Basque town of Zaldiba was required to entirely shut down due to the outbreak among educators. A spokesperson for the regional government said they could not confirm exactly how many teachers had contracted the virus or how long that school will remain closed. Every teacher in the school is being tested now. 

WestJet Airlines canceled a flight from Calgary to Toronto on Tuesday when tensions escalated on board after a family refused to obey the airline’s zero-tolerance mask policy, which requires all passengers over the age of 2 to wear a mask, according to the company. Safwan Choudhry said the airline staff was requiring his 19-month-old daughter to wear a mask despite her age, according to CBC, though a WestJet spokesperson confirmed it had been the family’s older 3-year-old daughter who had been the concern. Chouldry told CBC that his family had complied with the regulations with his older daughter wearing a mask, but WestJet told the news agency that accounts from the crew and airline agents differed from Chouldry’s account. “WestJet would like to clarify that there were two children, and we were not requiring the infant to wear a mask, but did require the other child, who is over age two, to wear one,” WestJet spokesperson Lauren Stewart told CBC in an email. Flight crews have access to a guest manifest, which specifically states which guests are two years of age, booking them as infants. 

The amount of Americans applying for unemployment benefits has stayed mostly unchanged with 884,000 claims filed in the last week. The steady numbers show signs that layoffs remain stuck at historic high levels six months after the pandemic shocked the economy, according to The Associated Press. The Labor Departments latest figures also show evidence that the improvement in the job market may be weakening despite solid gains in the summer months. In addition, hiring has slowed since June with a rising number of laid-off workers saying their job loss has become permanent. For the first time in six weeks, the amount of Americans receiving unemployment benefits rose week-to-week, to 13.4 million.

A recent video showed authorities in full hazmat gear arresting a woman who was surfing on a beach in Spain. AFP reported that the woman had recently tested positive for the coronavirus and had broken her quarantine orders. The unidentified woman was ordered to self-isolate but was caught surfing at San Sebastian beach in northern Spain, where she was taken into custody. Watch the video below.

Residents in California have had more than enough to worry about while dealing with record-breaking wildfires and evacuating from the fast-moving blazes. To only further complicate those worries, the pandemic has made evacuations “10 times harder,” one woman told AFP. Leanna Mikesler and her husband evacuated from their home in Meadow Lakes, located in the Sierra National Forest, to take shelter at a Red Cross facility in Clovis. The couple is staying in a subsidized hotel room because the usual emergency facility is no longer an option due to the coronavirus and social distancing efforts. The blazes have destroyed many homes and structures around the state, and evacuees have flooded shelters as evacuation plans, which sometimes include staying with a friend or relative, have become even more complicated since the beginning of the pandemic.

Gabe Huck, right, a member of a San Benito Monterey Cal Fire crew, stands along state Highway 168 while fighting the Creek Fire, Sunday, Sept. 6, 2020, in Shaver Lake, Calif. (AP Photo/Marcio Jose Sanchez)

A sumo stable in Tokyo has left 19 infected with the coronavirus after an outbreak spread through the stable, a governing body said Thursday. Despite the outbreak, a regularly scheduled tournament is scheduled to take place this week as planned. The Japan Sumo Association reported one wrestler and 18 trainees have tested positive for the virus, with 12 individuals taken to a hospital, according to France24. The sport suffered its first death from the virus in May after a 28-year-old contracted the virus. Seven of those that tested positive at the stable have no symptoms, while all that tested positive are isolated. The cluster comes amid Japan easing restrictions despite signs of an incoming second wave for the country.

After suffering a blowout loss to BYU, Navy football head coach Ken Niumatalolo blamed the loss on coronavirus concerns in practice. Niumatalolo said he was significantly against contact during fall camp to try and prevent potential spread of COVID-19, however after the loss, the team will go back to normal, full-contact practices despite the pandemic, according to ESPN. Players will go from once a week testing to twice a week COVID-19 testing to make players and staff more comfortable with bringing back full-contact practices. "We're probably the cleanest team in the country," Niumatalolo said, "but unfortunately we suck at football right now." The team's next game, against Temple, was postponed after a COVID-19 outbreak on Temples' roster.

The NFL regular season kicks off on Thursday night at Arrowhead Stadium as the Kansas City Chiefs host the Houston Texas. In 2014, fans at the stadium set a Guinness World Record for the loudest crowd at a sporting event at 142.2 decibels, but the roars from the crowd will be a fraction of that tonight. The stadium will be filled to 22% capacity, or around 16,000 fans, according to Fox news. Those that do watch the game in person will be spread out across the stadium, will need to wear a mask when not in their seats and will not be able to use cash to pay for any concessions. Spectators may also want to pack a poncho as rain is in the forecast during the game.

India set another daily record for most new positive cases recorded, as 95,735 new infections on Wednesday pushed the country's total to 4,465,863, the second-most in the world, according to The Associated Press. The Health Ministry also reported 1,172 new deaths in the past 24 hours, taking total fatalities to 75,062. The ministry said the surge in new infection is due to the increase in testing. However, experts warn that India might be experiencing a dangerous phase, as the virus is now spreading in smaller towns and villages. New Delhi, the Indian capital still remains the most affected city in the country. In the past 24 hours, the city saw a record surge of 4,618 new cases and 19 deaths.

Casinos are operating much differently in the age of COVID-19, and the coin shortage that has developed during the pandemic has left some casinos scrambling. The El Cortez Hotel & Casino in Las Vegas ordered $30,000 in quarters when reopening in July, but were only able to purchase $500 in quarters, NBC News said. One nearby casino has seen success with another method of dispensing winnings. Customers at The Cosmopolitan in Las Vegas have the option to print off a ticket with their winnings or to donate their change to charities, rather than receiving coins as a form of payout. "Since we reopened our doors following the mandatory COVID-19 closure earlier this year, we have seen record numbers in both the number of transactions and in monetary donations," said Chelle Adams, chief financial officer of The Cosmopolitan. "We are immensely thankful and proud of our guests' efforts in wanting to support our community throughout the trying current climate." Employees also have incentives for bringing in coins from home.

The United States will stop enhanced coronavirus screenings for travelers coming from international flights, Yahoo News reported. The screenings, which have been held in select airports since January, require passengers to provide contact information, which can be used to perform contact tracing. Additionally, passengers also receive temperature checks and are questioned about possible COVID-19 symptoms. However, starting Monday Sept. 14 at exactly 12:01 a.m., all screenings will cease, in accordance to the new White House mandate. Although no public announcements have been made yet, various agencies, including the Centers for Disease Control and Prevention, Customs and Border Protection and the Department of Homeland Security, are already preparing for Monday’s shutdown.

More than 6% of students at the University of Georgia have tested positive for COVID-19, a school where students are remaining on campus for in-person classes. The university reported over 1,400 new cases of COVID-19 over the past week, according The Associated Press. Over the past four weeks, there have been nearly 2,600 positive tests among the 39,000 students who attend the University of Georgia. “Each of us must make sound decisions in the coming days and weeks so that we can turn the trajectory, as we have seen at other institutions in the state,” said Jere Morehead, president of the University of Georgia.

Penn State Athletics paused all team activities for its programs after 48 student-athletes tested positive for the coronavirus between Aug. 31 and Sept. 4. The announcement came after the department administered 920 COVID-19 tests to athletes over that period of time. Although the department did not disclose which teams have been placed under quarantine, they specified that the transmission of COVID-19 did not occur during team activities. “Contact tracing is being performed and there is no evidence to suggest COVID-19 was transmitted during practice or training activities,” a press release said, according to StateCollege.com. Penn State’s COVID-19 dashboard, where the student-athlete cases were reported, also reported a total of 379 new cases among Penn State students at University Park between Aug. 31 and Sept. 6. 

NASA is using satellite imagery to track the impact of the pandemic lockdowns on the environment and researching how weather patterns could affect the spread of the virus. Researchers are planning to use satellite images to show the pandemic’s impacts on food security, fire ecology, urban surface heat, clouds and warming, air pollution and precipitation and water quality and aquatic ecosystems, NASA said in an announcement. Some of the studies include counting crops, tracking fire suppression and determining if less air pollution affects the amount of precipitation among other topics.

Here are the latest COVID-19 numbers, provided by researchers at Johns Hopkins University:

• Confirmed cases: 27,891,274

• Fatalities: 904,192

• Recoveries: 18,794,016

The global death toll from COVID-19 topped the 900,000 mark on Wednesday, less than 10 months after the outbreak began. The United States has seen more deaths than any other country, with 190,873, while Brazil, India, Mexico, and the United Kingdom round out the top five.

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