S
M
T
W
T
F
S
26
66°
56°
27
68°
54°
28
69°
49°
29
71°
52°
30
69°
58°
1
71°
55°
2
69°
60°
3
68°
60°
4
69°
58°
5
66°
55°
6
70°
56°
7
72°
58°
8
76°
57°
9
75°
59°
10
75°
58°
11
80°
60°
12
75°
59°
13
72°
60°
14
72°
58°
15
70°
57°
16
69°
58°
17
70°
59°
18
69°
59°
19
73°
54°
20
67°
53°
21
66°
54°
22
67°
53°
23
67°
54°
24
71°
58°
25
74°
58°
26
72°
56°
27
68°
54°
28
68°
54°
29
69°
55°
30
69°
56°
31
71°
59°
1
73°
60°
2
75°
59°
3
72°
58°
4
68°
58°
5
68°
60°
6
69°
59°
Temperature Graph
°F
Avg. Hi
Avg. Lo
Actual Hi
Actual Lo
Forecast Hi
Forecast Lo
May Weather in Serra Mesa
Serra Mesa's May 2026 forecast shows daily high temperatures ranging from 66° to 80°, with overnight lows between 53° and 60°. The average high for May is 71° with an average low of 57°. AccuWeather's monthly forecast extends further ahead than any other source, with day-by-day RealFeel® Temperatures giving a complete picture of how May weather will actually feel in Serra Mesa. See also: June | July | August.