S
M
T
W
T
F
S
26
65°
48°
27
73°
46°
28
70°
56°
29
62°
46°
30
56°
39°
1
53°
36°
2
50°
34°
3
59°
31°
4
72°
48°
5
64°
46°
6
56°
42°
7
59°
34°
8
64°
43°
9
72°
52°
10
72°
50°
11
68°
40°
12
74°
39°
13
64°
46°
14
64°
40°
15
64°
38°
16
72°
53°
17
83°
59°
18
85°
61°
19
85°
63°
20
68°
54°
21
66°
52°
22
61°
54°
23
72°
58°
24
77°
60°
25
77°
64°
26
76°
66°
27
74°
63°
28
77°
56°
29
79°
56°
30
75°
51°
31
70°
54°
1
73°
56°
2
73°
56°
3
74°
57°
4
76°
60°
5
78°
58°
6
75°
61°
Temperature Graph
°F
Avg. Hi
Avg. Lo
Actual Hi
Actual Lo
Forecast Hi
Forecast Lo
May Weather in Lake Santee
Lake Santee's May 2026 forecast shows daily high temperatures ranging from 70° to 79°, with overnight lows between 51° and 66°. The average high for May is 75° with an average low of 58°. AccuWeather's monthly forecast extends further ahead than any other source, with day-by-day RealFeel® Temperatures giving a complete picture of how May weather will actually feel in Lake Santee. See also: June | July | August.