S
M
T
W
T
F
S
26
67°
55°
27
68°
52°
28
73°
46°
29
76°
48°
30
72°
56°
1
78°
54°
2
78°
58°
3
69°
58°
4
69°
57°
5
67°
54°
6
73°
55°
7
74°
58°
8
78°
58°
9
79°
56°
10
78°
57°
11
82°
58°
12
76°
60°
13
75°
58°
14
76°
59°
15
75°
59°
16
73°
56°
17
74°
58°
18
73°
58°
19
76°
57°
20
70°
53°
21
71°
54°
22
70°
53°
23
71°
54°
24
75°
57°
25
78°
58°
26
76°
55°
27
72°
54°
28
72°
54°
29
73°
55°
30
74°
56°
31
75°
59°
1
78°
60°
2
79°
59°
3
76°
58°
4
72°
58°
5
73°
60°
6
74°
59°
Temperature Graph
°F
Avg. Hi
Avg. Lo
Actual Hi
Actual Lo
Forecast Hi
Forecast Lo
May Weather in La Mesa
La Mesa's May 2026 forecast shows daily high temperatures ranging from 70° to 82°, with overnight lows between 53° and 60°. The average high for May is 75° with an average low of 57°. AccuWeather's monthly forecast extends further ahead than any other source, with day-by-day RealFeel® Temperatures giving a complete picture of how May weather will actually feel in La Mesa. See also: June | July | August.