S
M
T
W
T
F
S
26
56°
41°
27
53°
41°
28
53°
36°
29
61°
33°
30
55°
39°
1
56°
32°
2
71°
30°
3
73°
46°
4
66°
43°
5
54°
32°
6
59°
26°
7
67°
32°
8
78°
43°
9
68°
42°
10
71°
34°
11
86°
42°
12
77°
50°
13
81°
41°
14
84°
55°
15
90°
47°
16
82°
48°
17
72°
45°
18
53°
43°
19
58°
37°
20
68°
46°
21
64°
48°
22
72°
51°
23
74°
54°
24
78°
55°
25
79°
56°
26
80°
60°
27
72°
54°
28
75°
55°
29
75°
58°
30
76°
53°
31
81°
58°
1
77°
59°
2
73°
58°
3
73°
56°
4
75°
59°
5
80°
60°
6
79°
60°
Temperature Graph
°F
Avg. Hi
Avg. Lo
Actual Hi
Actual Lo
Forecast Hi
Forecast Lo
May Weather in Santee
Santee's May 2026 forecast shows daily high temperatures ranging from 53° to 81°, with overnight lows between 37° and 60°. The average high for May is 73° with an average low of 54°. AccuWeather's monthly forecast extends further ahead than any other source, with day-by-day RealFeel® Temperatures giving a complete picture of how May weather will actually feel in Santee. See also: June | July | August.