S
M
T
W
T
F
S
29
84°
49°
30
85°
59°
31
83°
55°
1
74°
51°
2
78°
44°
3
80°
50°
4
67°
49°
5
71°
46°
6
69°
45°
7
71°
47°
8
82°
52°
9
88°
58°
10
86°
56°
11
82°
50°
12
78°
53°
13
78°
52°
14
79°
51°
15
78°
53°
16
82°
55°
17
85°
56°
18
86°
57°
19
87°
56°
20
79°
47°
21
80°
46°
22
72°
42°
23
75°
49°
24
83°
52°
25
84°
52°
26
84°
53°
27
83°
54°
28
83°
53°
29
82°
54°
30
83°
54°
1
80°
52°
2
77°
51°
Temperature Graph
°F
Avg. Hi
Avg. Lo
Actual Hi
Actual Lo
Forecast Hi
Forecast Lo
April Weather in Mesilla
Mesilla's April 2026 forecast shows daily high temperatures ranging from 71° to 88°, with overnight lows between 42° and 58°. The average high for April is 81° with an average low of 52°. AccuWeather's monthly forecast extends further ahead than any other source, with day-by-day RealFeel® Temperatures giving a complete picture of how April weather will actually feel in Mesilla. See also: May | June | July.