S
M
T
W
T
F
S
26
54°
28°
27
60°
29°
28
61°
31°
29
59°
36°
30
42°
36°
1
38°
27°
2
43°
24°
3
42°
27°
4
46°
23°
5
59°
35°
6
42°
32°
7
46°
32°
8
43°
30°
9
53°
28°
10
55°
34°
11
46°
29°
12
43°
27°
13
49°
24°
14
46°
36°
15
60°
39°
16
65°
40°
17
56°
37°
18
58°
46°
19
57°
51°
20
74°
36°
21
57°
41°
22
61°
39°
23
59°
44°
24
60°
47°
25
58°
46°
26
62°
48°
27
65°
48°
28
67°
51°
29
65°
50°
30
66°
48°
31
64°
54°
1
61°
43°
2
63°
45°
3
63°
46°
4
61°
47°
5
62°
48°
6
67°
48°
Temperature Graph
°F
Avg. Hi
Avg. Lo
Actual Hi
Actual Lo
Forecast Hi
Forecast Lo
May Weather in Saint-Louis
Saint-Louis's May 2026 forecast shows daily high temperatures ranging from 57° to 74°, with overnight lows between 36° and 54°. The average high for May is 63° with an average low of 46°. AccuWeather's monthly forecast extends further ahead than any other source, with day-by-day RealFeel® Temperatures giving a complete picture of how May weather will actually feel in Saint-Louis. See also: June | July | August.