S
M
T
W
T
F
S
26
83°
68°
27
73°
64°
28
78°
64°
29
80°
66°
30
84°
70°
1
84°
70°
2
79°
69°
3
83°
69°
4
78°
68°
5
79°
70°
6
84°
70°
7
83°
68°
8
77°
65°
9
77°
63°
10
76°
62°
11
75°
62°
12
76°
61°
13
76°
61°
14
77°
62°
15
81°
66°
16
82°
68°
17
82°
68°
18
81°
67°
19
81°
68°
20
79°
61°
21
73°
61°
22
72°
60°
23
73°
62°
24
74°
63°
25
77°
66°
26
80°
67°
27
80°
66°
28
79°
67°
29
82°
66°
30
83°
65°
31
74°
59°
1
73°
58°
2
72°
57°
3
72°
57°
4
73°
58°
5
73°
65°
6
75°
58°
Temperature Graph
°F
Avg. Hi
Avg. Lo
Actual Hi
Actual Lo
Forecast Hi
Forecast Lo
May Weather in Santa Cruz de la Sierra
Santa Cruz de la Sierra's May 2026 forecast shows daily high temperatures ranging from 72° to 84°, with overnight lows between 57° and 70°. The average high for May is 78° with an average low of 64°. AccuWeather's monthly forecast extends further ahead than any other source, with day-by-day RealFeel® Temperatures giving a complete picture of how May weather will actually feel in Santa Cruz de la Sierra. See also: June | July | August.