S
M
T
W
T
F
S
29
84°
49°
30
85°
59°
31
83°
55°
1
74°
51°
2
78°
44°
3
80°
50°
4
67°
49°
5
71°
46°
6
69°
45°
7
70°
48°
8
80°
42°
9
86°
45°
10
85°
55°
11
71°
51°
12
79°
47°
13
77°
51°
14
74°
52°
15
74°
40°
16
80°
37°
17
78°
48°
18
74°
49°
19
71°
48°
20
79°
43°
21
85°
47°
22
83°
58°
23
80°
51°
24
82°
48°
25
82°
50°
26
83°
49°
27
80°
44°
28
86°
63°
29
87°
64°
30
73°
56°
1
73°
49°
2
70°
47°
Temperature Graph
°F
Avg. Hi
Avg. Lo
Actual Hi
Actual Lo
Forecast Hi
Forecast Lo
April Weather in La Mesa
La Mesa's April 2026 forecast shows daily high temperatures ranging from 70° to 87°, with overnight lows between 47° and 64°. The average high for April is 78° with an average low of 56°. AccuWeather's monthly forecast extends further ahead than any other source, with day-by-day RealFeel® Temperatures giving a complete picture of how April weather will actually feel in La Mesa. See also: May | June | July.