S
M
T
W
T
F
S
29
82°
42°
30
83°
64°
31
86°
62°
1
86°
64°
2
80°
67°
3
87°
68°
4
79°
60°
5
67°
48°
6
73°
45°
7
76°
40°
8
81°
48°
9
81°
50°
10
83°
54°
11
85°
57°
12
81°
61°
13
83°
69°
14
85°
66°
15
86°
62°
16
86°
64°
17
86°
62°
18
79°
50°
19
74°
45°
20
77°
39°
21
76°
44°
22
80°
59°
23
84°
60°
24
84°
62°
25
80°
60°
26
87°
63°
27
88°
72°
28
N/A
29
73°
58°
30
67°
54°
1
58°
51°
2
65°
44°
Temperature Graph
°F
Avg. Hi
Avg. Lo
Actual Hi
Actual Lo
Forecast Hi
Forecast Lo
*Temporarily Unavailable
April Weather in La Mesa
La Mesa's April 2026 forecast shows daily high temperatures ranging from 58° to 73°, with overnight lows between 44° and 58°. The average high for April is 66° with an average low of 52°. AccuWeather's monthly forecast extends further ahead than any other source, with day-by-day RealFeel® Temperatures giving a complete picture of how April weather will actually feel in La Mesa. See also: May | June | July.