S
M
T
W
T
F
S
29
82°
68°
30
81°
64°
31
82°
64°
1
80°
65°
2
84°
65°
3
86°
66°
4
82°
66°
5
81°
66°
6
83°
65°
7
82°
66°
8
79°
68°
9
79°
66°
10
82°
65°
11
80°
64°
12
86°
66°
13
77°
64°
14
84°
64°
15
73°
64°
16
80°
64°
17
77°
63°
18
81°
66°
19
73°
64°
20
82°
61°
21
81°
66°
22
82°
64°
23
81°
64°
24
81°
65°
25
82°
64°
26
84°
66°
27
82°
64°
28
80°
65°
29
77°
66°
30
82°
66°
1
84°
65°
2
83°
65°
Temperature Graph
°F
Avg. Hi
Avg. Lo
Actual Hi
Actual Lo
Forecast Hi
Forecast Lo
April Weather in La Mesa
La Mesa's April 2026 forecast shows daily high temperatures ranging from 83° to 84°, with overnight lows between 65° and 65°. The average high for April is 84° with an average low of 65°. AccuWeather's monthly forecast extends further ahead than any other source, with day-by-day RealFeel® Temperatures giving a complete picture of how April weather will actually feel in La Mesa. See also: May | June | July.