S
M
T
W
T
F
S
27
75°
55°
28
82°
46°
29
86°
48°
30
91°
60°
1
93°
69°
2
72°
59°
3
76°
53°
4
82°
52°
5
79°
48°
6
79°
43°
7
86°
46°
8
85°
52°
9
88°
48°
10
74°
51°
11
85°
52°
12
90°
60°
13
91°
58°
14
79°
69°
15
88°
70°
16
71°
50°
17
60°
38°
18
67°
34°
19
72°
37°
20
74°
43°
21
75°
40°
22
77°
43°
23
76°
42°
24
76°
41°
25
77°
49°
26
77°
46°
27
72°
48°
28
76°
50°
29
78°
50°
30
79°
55°
31
75°
58°
Temperature Graph
°F
Avg. Hi
Avg. Lo
Actual Hi
Actual Lo
Forecast Hi
Forecast Lo
October Weather in Murphysboro
Murphysboro's October 2026 forecast shows daily high temperatures ranging from 72° to 79°, with overnight lows between 46° and 58°. The average high for October is 76° with an average low of 51°. AccuWeather's monthly forecast extends further ahead than any other source, with day-by-day RealFeel® Temperatures giving a complete picture of how October weather will actually feel in Murphysboro. See also: November | December | January.