S
M
T
W
T
F
S
26
74°
54°
27
73°
52°
28
72°
53°
29
69°
46°
30
66°
54°
1
67°
52°
2
71°
51°
3
69°
49°
4
72°
50°
5
75°
53°
6
77°
56°
7
78°
57°
8
78°
57°
9
77°
56°
10
78°
57°
11
71°
55°
12
72°
57°
13
76°
58°
14
76°
51°
15
71°
52°
16
74°
56°
17
79°
59°
18
74°
52°
19
74°
51°
20
75°
52°
21
73°
54°
22
74°
53°
23
73°
61°
24
79°
62°
25
84°
62°
26
84°
61°
27
85°
63°
28
84°
64°
29
87°
64°
30
86°
56°
31
83°
56°
1
78°
59°
2
83°
64°
3
85°
64°
4
84°
62°
5
87°
56°
6
80°
56°
Temperature Graph
°F
Avg. Hi
Avg. Lo
Actual Hi
Actual Lo
Forecast Hi
Forecast Lo
May Weather in Murphysboro
Murphysboro's May 2026 forecast shows daily high temperatures ranging from 66° to 87°, with overnight lows between 46° and 64°. The average high for May is 77° with an average low of 56°. AccuWeather's monthly forecast extends further ahead than any other source, with day-by-day RealFeel® Temperatures giving a complete picture of how May weather will actually feel in Murphysboro. See also: June | July | August.