S
M
T
W
T
F
S
26
83°
62°
27
82°
63°
28
64°
52°
29
67°
47°
30
68°
47°
1
70°
45°
2
72°
45°
3
84°
47°
4
81°
58°
5
71°
49°
6
65°
44°
7
74°
40°
8
83°
49°
9
85°
47°
10
65°
53°
11
78°
45°
12
83°
47°
13
84°
55°
14
85°
62°
15
86°
77°
16
87°
70°
17
88°
70°
18
90°
75°
19
79°
54°
20
61°
54°
21
65°
56°
22
79°
60°
23
79°
60°
24
83°
57°
25
87°
56°
26
83°
60°
27
80°
64°
28
83°
66°
29
86°
70°
30
92°
71°
31
97°
71°
1
97°
70°
2
87°
68°
3
80°
64°
4
81°
67°
5
84°
65°
6
83°
64°
Temperature Graph
°F
Avg. Hi
Avg. Lo
Actual Hi
Actual Lo
Forecast Hi
Forecast Lo
May Weather in Depew
Depew's May 2026 forecast shows daily high temperatures ranging from 80° to 97°, with overnight lows between 64° and 71°. The average high for May is 87° with an average low of 68°. AccuWeather's monthly forecast extends further ahead than any other source, with day-by-day RealFeel® Temperatures giving a complete picture of how May weather will actually feel in Depew. See also: June | July | August.