S
M
T
W
T
F
S
29
68°
36°
30
77°
45°
31
79°
50°
1
82°
55°
2
81°
55°
3
79°
58°
4
81°
54°
5
81°
63°
6
64°
45°
7
70°
47°
8
65°
42°
9
72°
48°
10
78°
48°
11
83°
54°
12
83°
57°
13
82°
57°
14
85°
58°
15
86°
63°
16
85°
60°
17
84°
61°
18
84°
62°
19
83°
63°
20
84°
52°
21
81°
57°
22
81°
58°
23
82°
58°
24
82°
57°
25
81°
58°
26
80°
58°
27
82°
57°
28
79°
58°
29
78°
57°
30
75°
56°
1
76°
59°
2
76°
56°
Temperature Graph
°F
Avg. Hi
Avg. Lo
Actual Hi
Actual Lo
Forecast Hi
Forecast Lo
April Weather in Santee
Santee's April 2026 forecast shows daily high temperatures ranging from 65° to 86°, with overnight lows between 42° and 63°. The average high for April is 80° with an average low of 56°. AccuWeather's monthly forecast extends further ahead than any other source, with day-by-day RealFeel® Temperatures giving a complete picture of how April weather will actually feel in Santee. See also: May | June | July.