S
M
T
W
T
F
S
29
67°
30°
30
73°
54°
31
81°
62°
1
79°
55°
2
84°
60°
3
81°
58°
4
79°
49°
5
64°
38°
6
65°
38°
7
58°
35°
8
66°
41°
9
70°
43°
10
73°
46°
11
75°
53°
12
74°
54°
13
73°
51°
14
69°
50°
15
71°
40°
16
72°
45°
17
64°
42°
18
66°
43°
19
69°
44°
20
74°
47°
21
74°
48°
22
75°
48°
23
75°
49°
24
76°
49°
25
76°
50°
26
75°
40°
27
69°
38°
28
64°
40°
29
70°
48°
30
67°
44°
1
66°
41°
2
67°
42°
Temperature Graph
°F
Avg. Hi
Avg. Lo
Actual Hi
Actual Lo
Forecast Hi
Forecast Lo
April Weather in Middlesboro
Middlesboro's April 2026 forecast shows daily high temperatures ranging from 58° to 84°, with overnight lows between 35° and 60°. The average high for April is 71° with an average low of 46°. AccuWeather's monthly forecast extends further ahead than any other source, with day-by-day RealFeel® Temperatures giving a complete picture of how April weather will actually feel in Middlesboro. See also: May | June | July.