S
M
T
W
T
F
S
26
78°
62°
27
78°
49°
28
72°
53°
29
76°
60°
30
73°
50°
1
64°
44°
2
69°
47°
3
68°
50°
4
67°
53°
5
82°
58°
6
67°
56°
7
69°
52°
8
69°
50°
9
70°
51°
10
70°
52°
11
75°
61°
12
72°
61°
13
80°
55°
14
72°
53°
15
71°
52°
16
71°
52°
17
72°
53°
18
73°
60°
19
73°
59°
20
74°
55°
21
73°
54°
22
74°
55°
23
75°
59°
24
76°
62°
25
75°
57°
26
75°
58°
27
76°
60°
28
76°
64°
29
75°
64°
30
77°
60°
31
77°
60°
1
78°
61°
2
78°
61°
3
79°
62°
4
81°
65°
5
86°
66°
6
90°
67°
Temperature Graph
°F
Avg. Hi
Avg. Lo
Actual Hi
Actual Lo
Forecast Hi
Forecast Lo
May Weather in Cape Girardeau
Cape Girardeau's May 2026 forecast shows daily high temperatures ranging from 64° to 90°, with overnight lows between 44° and 67°. The average high for May is 74° with an average low of 57°. AccuWeather's monthly forecast extends further ahead than any other source, with day-by-day RealFeel® Temperatures giving a complete picture of how May weather will actually feel in Cape Girardeau. See also: June | July | August.
