As the first real push of Arctic air arrives Tuesday, it will set the stage for snow and slippery travel around Pittsburgh.
Motorists, school districts and airline passengers should anticipate travel delays due to snow, poor visibility and slippery conditions spanning early Tuesday morning into part of the afternoon rush hour.
Temperatures will dip to just below freezing by Tuesday morning and struggle to rise much during the day Tuesday.
Any areas that remain wet during the day Tuesday can become icy at night, unless treated.
While only a general coating to an inch of snow is forecast, where lake-effect snow persists there can be several inches.
In addition to some snow accompanying the passage of an arctic cold front, a band of lake-effect snow is likely to extend southward from Lake Huron, across Lake Erie and into western Pennsylvania, part of West Virginia and western Maryland Tuesday.
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The NFL will continue its time-honored tradition of playing on Thanksgiving Day with three games that will help shape the league's playoff picture.
A break from the waves of cold air hammering the Midwest and Northeast is on the way, but not until next week.
A potential windstorm will unfold over the United Kingdom on Wednesday, bringing widespread wet and windy conditions to the region.
The 91st annual Macy's Thanksgiving Day Parade will take place this Thursday morning with sunshine and chilly conditions expected.
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Nationwide, most parades will occur rain or shine, but the parade team must make adjustments for conditions such as wind, rain, snow and low temperatures.
The busiest travel week of the year also falls during a volatile time for extreme weather.