Largo police have shut down the southbound lanes of U.S. Highway 19 at East Bay Drive.
Officials described it as a "serious crash." FOX 13 traffic reporter Vanessa Ruffes recommends Belcher Road or Bayside Bridge as detours.
SkyFOX aerials showed traffic backed up for a couple of miles by 6:15 a.m. with cars being diverted onto Frontage Road.
No other information was immediately provided, including how long the lane closure will last. Police said a media release will be issued with more details.
This is a developing story. Stay with FOX 13 for the latest.