There is the risk of strong to locally severe thunderstorms for a time Wednesday night from northern Louisiana to southern Illinois.
The greatest risks from the storms will be strong wind gusts and hail, as well as flash and urban flooding.
Cities that could be hit by the strong storms and their gusty winds and blinding downpours include Little Rock, Ark.; Memphis, Tenn.; Tupelo, Miss.; Monroe, La., Cape Girardeau, Mo.; Louisville, Ky.; and Evansville, Ind.
Even as the potential for severe thunderstorms decreases after midnight, showers and locally heavy, gusty thunderstorms will continue along an advancing front as it pushes to the east through Thursday.
There is a slight chance of a couple of the strongest storms producing a tornado.
A strong flow of air behind the front can bring damaging wind gusts even without thunderstorms.
There is the potential for nearly hurricane-force wind gusts in the clear air spanning thousands of square miles expanding from the northern Rockies to the northern and central Plains during the middle of the week.
Very blustery conditions are likely to sweep into the middle Mississippi and Ohio valleys Wednesday night and Thursday in the wake of the front.
Throughout the United States, the greatest potential for the weather to disrupt outdoor plans and festivities on Easter Sunday exists across the Plains.
A low pressure system has begun to spread heavy rain over parts of the Southeast, bringing the risk of flooding to the area.
At least 12 are dead and three are still missing after an avalanche cascaded down a climbing route on Mount Everest early Friday morning.
Showers across much of Europe will make for a soggy day or two through the Easter holiday.
While Pittsburgh will start the weekend on a mild note, even warmer air is expected for Easter Sunday.
Dry weather from Easter weekend will hold through Monday in Boston for Patriots' Day and the 118th annual Boston Marathon.
SE Virginia (1983)
4" snow at Hampton, 3" snow at Newport News (heaviest snowfalls on record so late in the season).
Colorado Rockies (1992)
Big spring snowstorm... 12" at Vail 8" at Winter Park 10" at Copper Mountain 8" at Aspen
South Dakota (1995)
Spring snows continued. 6-12" and locally 2 feet fell between Mobridge and Aberdeen. A stretch of I-90 had to be closed.