There is the risk of strong to locally severe thunderstorms for a time Wednesday night from northern Louisiana to southern Illinois.
The greatest risks from the storms will be strong wind gusts and hail, as well as flash and urban flooding.
Cities that could be hit by the strong storms and their gusty winds and blinding downpours include Little Rock, Ark.; Memphis, Tenn.; Tupelo, Miss.; Monroe, La., Cape Girardeau, Mo.; Louisville, Ky.; and Evansville, Ind.
Even as the potential for severe thunderstorms decreases after midnight, showers and locally heavy, gusty thunderstorms will continue along an advancing front as it pushes to the east through Thursday.
There is a slight chance of a couple of the strongest storms producing a tornado.
A strong flow of air behind the front can bring damaging wind gusts even without thunderstorms.
There is the potential for nearly hurricane-force wind gusts in the clear air spanning thousands of square miles expanding from the northern Rockies to the northern and central Plains during the middle of the week.
Very blustery conditions are likely to sweep into the middle Mississippi and Ohio valleys Wednesday night and Thursday in the wake of the front.
After a period of above-average temperatures across most of the Midwest and Northeast last week, a complete reversal in the weather pattern will move in this week.
A new round of thunderstorms will bring the risk of severe weather across parts of Texas and Oklahoma to the lower Mississippi Valley by the middle of the week.
Due to the positive feedback, the National Weather Service has expanded their former, experimental Impact Based Warnings to include the Southern region for the spring of 2015.
As residents are far from over with the recent cold winter across the Great Lakes, Mother Nature will bring the return of snowflakes to the region this week.
Global warming and climate change, two terms that are treated synonymously in most media coverage and casual debate, have been shown to spark different reactions from the American public.
Following strong to locally severe thunderstorms in part of the South Central states at midweek, the risk of violent storms will increase over the region on Friday.
Eastern New England (1991)
Deepening coastal storm: central pressure near 29.00", 55 mph winds and 3.32" of rain at Boston. Portland, ME, had 1.54" of rain in three hours. Two homes in Manchester, NH, partially unroofed. Wind gust to 128 mph on Mt. Washington. Final rain total for Portland was 4.21".
Greensboro, NC (1992)
Rainfall of 3.87".
Afton, VA (1992)
Dense fog caused a 50 vehicle pile up; two people were killed, and dozens were injured.