There is the risk of strong to locally severe thunderstorms for a time Wednesday night from northern Louisiana to southern Illinois.
The greatest risks from the storms will be strong wind gusts and hail, as well as flash and urban flooding.
Cities that could be hit by the strong storms and their gusty winds and blinding downpours include Little Rock, Ark.; Memphis, Tenn.; Tupelo, Miss.; Monroe, La., Cape Girardeau, Mo.; Louisville, Ky.; and Evansville, Ind.
Even as the potential for severe thunderstorms decreases after midnight, showers and locally heavy, gusty thunderstorms will continue along an advancing front as it pushes to the east through Thursday.
There is a slight chance of a couple of the strongest storms producing a tornado.
A strong flow of air behind the front can bring damaging wind gusts even without thunderstorms.
There is the potential for nearly hurricane-force wind gusts in the clear air spanning thousands of square miles expanding from the northern Rockies to the northern and central Plains during the middle of the week.
Very blustery conditions are likely to sweep into the middle Mississippi and Ohio valleys Wednesday night and Thursday in the wake of the front.
Travel hazards, delays and disruptions associated with rain, ice and snow will continue over the Central states through the balance of the Thanksgiving weekend.
Following a mild Thanksgiving and Black Friday, noticeably cooler air will return to the Northeast this weekend.
Sandra remains on track to make landfall in northern Mexico on Saturday, but it will be much weaker than its current major hurricane status.
The current reprieve from heavy rain across southern India will not last long with the threat for flooding downpours set to return for the final days of November.
A major Thanksgiving Day storm threatens to ruin holiday events across the Central states with flooding rain, snow, a glaze of ice and fog.
Compared to Thanksgiving Day in 2014, this Thanksgiving will be substantially warmer in the Northeast.
Philadelphia, PA (1976)
Last of 23 straight days without any measurable precipitation.
Thanksgiving Weekend blizzard begins. A total of 21.5 inches of snow in Denver (26th-27th). Zero visibility at Limen, Co, for 24 consecutive hours.
New England (1888)
Hurricane passed inside Nantucket over Cape Cod. Later crossed Nova Scotia Block Island- 84 mph wind gust.