The first accumulating snow of the season is spreading through areas from Indiana into Lower Michigan, including Fort Wayne and Detroit.
Through Wednesday morning, snow will continue falling and expanding across the region.
The snow is heavy and wet in nature and has already taken down trees and caused power outages across portions of Indiana.
East of the snow is drenching rain spreading from south to north over the Northeast, as cautioned by Senior Meteorologist Kristina Pydynowski this past weekend.
During the transition from rain to snow, sleet can fall for a time.
The storm produced snow in very unlikely places such as Memphis and Jackson, Tenn., and Huntsville, Ala., Tuesday morning.
While the snow has had trouble sticking to roads in the South as anticipated, it will make for slippery travel farther north over portions of Indiana, lower Michigan, northwestern Ohio and central Ontario.
Parts of central Michigan and northern Indiana had already picked up 9 inches of snow by midnight EST Wednesday.
The snow may fail to accumulate much on inner city roads, but slippery and slushy conditions can develop in outlying areas and on bridges and overpasses where road surface temperatures are lower.
West of the heavy snow area, around Chicago, some wet areas can freeze before drying off late tonight. Strong winds and lake shore flooding were occurring on the southern end of Lake Michigan today with the powerful storm.
Pedestrians and motorists should be alert for areas of black ice Wednesday morning as a result. Temperatures will plunge into the teens and 20s over a large part of the Midwest in the wake of the storm.
The pattern into the end of the week will deliver the coldest nights of the season so far to many places in the region.
After what has been an unusually warm November for much of the East, it seems some areas will catch up a bit on snow in the last few days of the month.
A swath of 3- to 6-inch snowfall will emerge over part of northern Indiana and northwestern Ohio to the shores of Lake Huron in Michigan into Wednesday, including part of the I-80/90 corridor.
Flight delays are possible at Detroit, even though the heaviest snow from the storm will fall just north and west of these metro areas.
The band of heavy snow will remain east of Chicago and will stay well northwest of Cincinnati and Cleveland.
As the storm rolls northward and cold air circulates around the back side, accumulating snow will also fall over part of the central Appalachians. Up to a few inches of snow can fall on the mountains of West Virginia, western Virginia, the high ground in the Maryland Panhandle and south-central Pennsylvania Wednesday.
The zones of accumulating snow are challenging as this is a rather strangely configured storm for November. The storm will have an invading dry, warm pocket of air in the heart of the snow area.
Warmth will continue to be flung into Maine, while cold air and snow will greet the interior South.
Heavy, windswept rain from the South will roll through New England into Wednesday morning causing substantial travel delays.
This story was first published Monday, Nov. 28, 2011 at 11:30 a.m. EST. with the title "Snow Heading for Detroit, Indianapolis, Midwest."
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