The High Plains and portions of Texas will become the targets of spotty, but violent storms Friday evening.
Northeastern Colorado, northwestern Kansas and western Nebraska have the greatest threat for very large hail and tornadoes.
Damaging wind gusts higher than 60 mph, frequent lightning and locally flooding downpours are other concerns.
Meanwhile, thunderstorms will stretch southward to Texas during the evening. Torrential downpours appears to be the biggest concern with the storms that will erupt across west-central and southern Texas. However, damaging wind, large hail and isolated tornadoes can also occur in the strongest storms that develop. San Antonio is among the communities at risk for violent thunderstorms.
The threat of spotty late afternoon and evening severe storms in the High Plains exists through the Memorial Day weekend. It is crucial for those celebrating the holiday with outdoor festivities to stay alert of the possibility of rapidly changing weather conditions. Check back frequently with the AccuWeather Severe Weather Center for severe thunderstorm watches and warnings.
A more organized and widespread severe storm risk will arrive by the middle of next week.
"There is a possibility of a severe weather outbreak beginning Wednesday over the High Plains, spreading eastward over the lower Plains and Mississippi Valley Thursday into Friday," AccuWeather Expert Senior Meteorologist Alex Sosnowski said.
Tropical moisture may put outdoor Memorial Day plans in jeopardy from Washington D.C., to Boston on Monday.
As millions prepare to take part in Memorial Day weekend events, showers, storms and a potential tropical system could threaten outdoor activities and travel plans during the extended weekend.
Tropical Depression Two has developed northeast of the Bahamas and will approach the southeastern coast of the United States with downpours, building surf and an increasing breeze during Memorial Day weekend.
Severe weather, including the risk of flash flooding and a few tornadoes, will continue into Memorial Day weekend.
South East England will face rain threaten to ruin Monday's bank holiday, while the rest of the United Kingdom enjoys another mostly dry and mild day.
Violent storms whirled through the central United States this week, spawning large tornadoes on multiple days.
Jarrell, TX (1997)
F5 tornado obliterated most of town. Twister was 3/4 mile wide. Cattle were thrown 1/4 mile. About 30 people were killed.
Great James River flood; 150 lives lost in Richmond area.
St. Louis, MO (1896)
Great St. Louis tornado; 306 killed, $13 million damage.